NFL 2025-26: Week 12 #2 Regular Season Predictions

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(EDITOR'S NOTE: A lot of information posted here in this story is from statmuse.com, so please go use Statmuse for yourself to find any sports statistics and scores about all of your favorite athletes and teams in every major professional sport and strongly consider giving them your money to use their service for more detailed information if you already really like what you see when you use their services for free!)

(ADDITIONAL NOTE, VERY IMPORTANT!: This IS NOT the post/story for the Thursday Night, Sunday Morning and the early Sunday afternoon games! This is the second post/story for the Sunday late afternoon, Sunday Night and Monday Night games! I may post my notes for the Thursday Night, Sunday Morning and early Sunday afternoon games here in this post/story here briefly/momentarily for a few days so I don't accidentally delete the notes in my other post/story (Post #1)! So, I am forced to split up my story into parts because for some odd reason my post/story is too long! Honestly, I think the real reason is that the computer that I am using is just way too slow! To read about the Thursday Night, Sunday Morning and early Sunday afternoon games in REGULAR SEASON Week 12 click here on my personal website: https://ogeagleet852.wixsite.com/evantroxel/single-post/nfl-2025-26-week-12-1-regular-season-predictions)

By: Evan Troxel

These are my predictions to win and lose for the 2025-26 National Football League season for Regular Season Week 12 from Thursday, November 20th, 2025, through Monday, November 24th, 2025!

Please follow me on Gab.com at Gab.com/EvanTroxel and on Telegram at t.me/Evan_Troxel for my re-predictions before game time and my FINAL predictions to win and lose all games in REGULAR SEASON Week 12 and in every week of the National Football League all season long if I don't post them right here in this story!

NFL 2025-26 Regular Season Week 12 Predictions 

The Denver Broncos, Los Angeles Chargers, Miami Dolphins, Washington Commanders are on a bye week this week!

Now that we've gotten that out of the way, these are the referee assignments for REGULAR SEASON Week 12 on footballzebras.com!: https://www.footballzebras.com/2025/11/week-12-referee-assignments-2025/

Thursday, November 20th, 2025

Thursday Night Football, 6:15 p.m. Eastern Time (Prime Video)

Buffalo Bills at Houston Texans

Bills 7-3 (2-2 away) this season

Bills 493-508-8 (-15 more wins, 1,009 games played, W1) all-time won-lost record REGULAR SEASON

Bills 207-291-4 (-84 more wins, 502 games played, L1) all-time won-lost record REGULAR SEASON AWAY

Bills 514-530-8 (-16 more wins, 1,052 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

Bills 211-306-4 (-95 more wins, 521 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Bills have a winning and losing streak of W0 for the four categories above.

Prime numbers section

-The Bills have been unsuccessful once this season (0-1) in picking up their 509th loss (again loss, not win) in the regular season all-time because of their win vs. the Buccaneers on November 16th, 2025! So, if they Bills do that again this week their won-lost record will be 2-0 when trying to get their 509th loss in the regular season all-time!

-The Bills haven't had a tie game in away games so far this season (0-4) to get their 5th tie all-time in the regular season AWAY. The Bills are 2-0 this season when they can be -83 games below .500 all-time in the regular season away! They can do that again with a win on Sunday! The Bills are also 1-0 this season in prime number games! They won their 499th game all-time away in their first road game this regular season at the New York Jets on Sunday, September 14th!

-The Bills have been successful every single time this season (5-0) to get either -17 or -19 more wins all-time won-lost record in the regular season and postseason. If the Bills are successful again, they will lose against the Texans on Thursday Night. The Bills won-lost record has been 3-2 for this specific criteria! One of the "successes" didn't really count either way as it could have hit -17 or -19 when they played at the Panthers earlier this season (they were -18 more wins before the Panthers game, which the Bills won by the way), so instead of being at -19 more wins (with a loss) when they played the Panthers it moved up to -17 more wins (since the Bills won)! They can get -17 more wins with a loss at Houston on Thursday Night! The Bills won their only away game after a loss for this specific information in this paragraph which could mean absolutely nothing in the big picture. Also, this will be the Bills third straight away game to "hit" for this specific criteria which could be a bad sign for a Bills win when they lost their second away game (their first loss away at Miami) this season (for this specific information, they lost a home game vs. New England earlier this season) at Miami and two and three are prime numbers! Versus Carolina it was Buffalo's 1,049th game all-time and at Miami it was Buffalo's 1,051st game in the regular season and postseason all-time! The next prime game number is 1,061, which will be the Divisional round of the playoffs or the AFC Championship Game if the Bills get that far this season! The only other thing worth saying about this is that if this is an every other thing or an every two thing based on their current pattern for this specific info, the Bills will win on Thursday Night. So these notes should be summarized in this paragraph as likely a Bills loss at Houston on Thursday Night for this specific criteria!

-The Bills don't have a won-lost record this season for hitting (or not hitting) prime numbers in the regular season and postseason away and if they lose at Houston it will be their 307th loss which is the 63rd prime number. The Bills are also 0 for 4 in getting their fifth tie all-time in regular season and postseason away games! What people do need to pay attention to AT Pittsburgh next week on Sunday, November 30th, is that the Bills lost their 521st game at Miami earlier this season and the Bills will be playing game #523 all-time (against any NFL team, other than themselves of course) against Pittsburgh!

To summarize the prime numbers section, I would say Buffalo has a slight advantage to win over the Texans if I/we are not trying to count the same thing twice! The Bills I would say have a 3 to 1 advantage for the hardline stance in the paragraphs above! If you want to get more specific, I would say the Bills probably have a 6 to 4 advantage over the Texans to win!

Stats updated/corrected on Tuesday, November 18th, 2025, after the regular season Week 11 games in the 2025-26 season

Bills 6-4 (+2 more wins, 10 games played, W2) on November 20th all-time won-lost record

Bills 3-2 (+1 more wins, 5 games played, W1) all-time won-lost record on November 20th AWAY

Bills 15-10-1 (+5 more wins, 26 games played, W8) all-time won-lost record REGULAR SEASON on Thursdays

Bills 11-7-1 (+4 more wins, 19 games played, W6) all-time won-lost record REGULAR SEASON on Thursdays AWAY

Bills 8-6-1 (+2 more wins, 15 games played, W3) all-time won-lost record REGULAR SEASON on Thursdays in November

Bills 7-6-1 (+1 more wins, 14 games played, W3) all-time won-lost record REGULAR SEASON on Thursdays in November AWAY

Bills 127-136-4 (-9 more wins, 267 games played, W1) all-time won-lost record REGULAR SEASON in November

Bills 57-82-3 (-25 more wins, 142 games played, L1) all-time won-lost record REGULAR SEASON in November AWAY

Bills 315-343-1 (-28 more wins, 659 games played, L1) against the AFC all-time in the regular season

Bills 131-195-1 (-64 more wins, 327 games played, L1) against the AFC AWAY all-time in the regular season

Bills 22-25 (-3 more wins, 47 games played, W2) against the AFC South all-time in the regular season

Bills 8-15 (-7 more wins, 23 games played, W1) against the AFC South AWAY all-time in the regular season

The Bills have a winning percentage at or above .500 for SIX of the above twelve data points. The Bills are currently on a winning streak for NINE of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W24.

Houston Texans 5-5 (3-2 home) this season

Houston Texans all-time won-lost records BEFORE regular season Week 12 in the 2025-26 National Football League season!:

167-214-1 (-47 more wins, 382 games played, W2) all-time won-lost record REGULAR SEASON

95-95-1 (+0 more wins, 191 games played, W1) all-time won-lost record REGULAR SEASON HOME

173-222-1 (-49 more wins, 396 games played, W2) all-time won-lost record REGULAR SEASON and POSTSEASON

101-97-1 (+4 more wins, 199 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Texans have a combined winning and losing streak of W6 for the four categories above!

Texans 0-2 (-2 more wins, 2 games played, L2) all-time won-lost record on November 20th

Texans 0-2 (-2 more wins, 2 games played, L2) on November 20th HOME

Texans 6-10 (-4 more wins, 16 games played, L3) all-time won-lost record on Thursdays regular season

Texans 3-4 (-1 more wins, 7 games played, L2) all-time won-lost record on Thursdays HOME regular season

Texans 3-1 (+2 more wins, 4 games played, L1) all-time won-lost record on Thursdays in November regular season

Texans 1-1 (+0 more wins, 2 games played, L1) all-time won-lost record on Thursdays in November HOME regular season

41-49 (-8 more wins, 90 games played, W2) all-time won-lost record in November regular season

20-25 (-5 more wins, 45 games played, W1) all-time won-lost record in November HOME regular season

130-151-1 (-21 more wins, 282 games played, W2) all-time won-lost record against AFC regular season

70-70-1 (+0 more wins, 141 games played, W1) all-time won-lost record against AFC HOME regular season

22-25 (-3 more wins, 47 games played, W1) all-time won-lost record against AFC East regular season

14-9 (+5 more wins, 23 games played, W2) all-time won-lost record against AFC East HOME regular season

The Texans are at or above a .500 winning percentage for FOUR of the 12 categories above. The Texans have a winning streak for SIX of the 12 categories above. The Texans have a combined winning and losing streak for the 12 categories above of L2.

Bills 5-6 (-1 more wins, 11 games played, L1) all-time won-lost record against Texans

Bills 2-4 (-2 more wins, 6 games played, L4) all-time won-lost record against Texans AWAY

The Bills have never played against the Texans on November 23rd all-time.

The Bills have never played against the Texans on November 23rd AWAY all-time.

The Bills have never played against the Texans on Thursdays all-time REGULAR SEASON.

The Bills have never played against the Texans on Thursdays AWAY all-time REGULAR SEASON.

Bills have never played against Texans on Thursdays in November

Bills have never played against Texans AWAY on Thursdays in November

Bills 1-3 (-2 more wins, 4 games played, L2) against Texans all-time won-lost record in November

Bills 1-1 (+0 more wins, 2 games played, L1) against Texans all-time won-lost record in November AWAY.

The Bills have never played against the Texans all-time in Week 12, according to Statmuse.com.

The Bills have never played against the Texans all-time AWAY in Week 12, according to Statmuse.com.

The Bills against the Texans have a winning percentage at or above .500 for ONE of the above twelve data points. The Bills against the Texans are currently on a winning streak for ZERO of the 12 data points listed above. The Bills have a combined winning and losing streak against the Texans of L8 based on all of the criteria after the 12 points criteria for each team.

All-time won-lost records for quarterbacks

Josh Allen (BUF):

83-38 (+45 more wins, 121 games played, W1) regular season

90-44 (+46 more wins, 134 games played, W1) regular season and postseason

35-24 (+11 more wins, 59 games played, L1) regular season AWAY

35-28 (+7 more wins, 63 games played, L1) regular season and postseason AWAY

1-2 (-1 more wins, 3 games played, L1) regular season against Texans

0-2 (-2 more wins, 2 games played, L2) regular season AWAY against Texans

1-3 (-2 more wins, 4 games played, L1) regular season and postseason against Texans

0-3 (-3 more wins, 3 games played, L3) regular season and postseason AWAY against Texans

Davis Mills (HOU):

14-27-1 (-13 more wins, 42 games played, W2) regular season

15-27-1 (-12 more wins, 43 games played, W2) regular season and postseason

5-15-1 (-10 more wins, 21 games played, W1) regular season HOME

6-15-1 (-9 more wins, 22 games played, W1) regular season and postseason HOME

0-1 (-1 more wins, 1 games played, L1) regular season against Bills

0-1 (-1 more wins, 1 games played, L1) regular season and postseason against Bills

Not an OFFICIAL prediction yet!:

Likely prediction to win: Buffalo Bills

Likely prediction to lose: Houston Texans

Results:

New York Jets at Baltimore Ravens

Jets 435-567-8 (-132 more wins, 1,010 games played, L1) all-time won-lost record REGULAR SEASON

Jets 193-309-3 (-116 more wins, 505 games played, L1) all-time won-lost record REGULAR SEASON AWAY

Jets 447-580-8 (-133 more wins, 1,035 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON

Jets 201-319-3 (-118 more wins, 523 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Jets have a winning and losing streak of L4 for the four categories above.

Jets 6-2 (+4 more wins, 8 games played, W4) on November 23rd all-time won-lost record

Jets 1-1 (+0 more wins, 2 games played, W1) all-time won-lost record on November 23rd AWAY

Jets 377-476-4 (-99 more wins, 857 games played, W2) all-time won-lost record REGULAR SEASON on Sundays

Jets 169-265-2 (-96 more wins, 436 games played, W1) all-time won-lost record REGULAR SEASON on Sundays AWAY

Jets 108-118 (-10 more wins, 226 games played, W1) all-time won-lost record REGULAR SEASON on Sundays in November

Jets 45-57 (-12 more wins, 102 games played, L4) all-time won-lost record REGULAR SEASON on Sundays in November AWAY

Jets 119-137 (-18 more wins, 256 games played, L1) all-time won-lost record REGULAR SEASON in November

Jets 49-69 (-20 more wins, 118 games played, L5) all-time won-lost record REGULAR SEASON in November AWAY

Jets 282-377-2 (-95 more wins, 661 games played, L1) against the AFC all-time in the regular season

Jets 123-206-1 (-83 more wins, 330 games played, L1) against the AFC AWAY all-time in the regular season

Jets 22-25 (-3 more wins, 47 games played, W2) against the AFC North all-time in the regular season

Jets 8-15 (-7 more wins, 23 games played, W1) against the AFC North HOME all-time in the regular season

The Jets have a winning percentage at or above .500 for TWO of the above twelve data points. The Jets are currently on a winning streak for SEVEN of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W0.

Baltimore Ravens:

273-204-1 (+69 more wins, 478 games played, W4) all-time won-lost record REGULAR SEASON

162-76-1 (+86 more wins, 239 games played, W3) all-time won-lost record REGULAR SEASON HOME

291-218-1 (+73 more wins, 510 games played, W4) all-time won-lost record REGULAR SEASON and POSTSEASON

167-81-1 (+86 more wins, 249 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Ravens have a combined winning and losing streak of W14 for the four categories above!

2-1 (+1 more wins, 3 games played, W2) all-time won-lost record on November 23rd

2-1 (+1 more wins, 3 games played, W2) all-time won-lost record on November 23rd HOME

233-179-1 (+54 more wins, 413 games played, W3) all-time won-lost record on Sundays regular season

141-70-1 (+71 more wins, 212 games played, W1) all-time won-lost record on Sundays HOME regular season

62-42-1 (+20 more wins, 105 games played, W2) all-time won-lost record on Sundays in November regular season

38-16-1 (+22 more wins, 55 games played, W1) all-time won-lost record on Sundays in November HOME regular season

75-46-1 (+29 more wins, 122 games played, W3) all-time won-lost record in November regular season

44-16-1 (+28 more wins, 61 games played, W3) all-time won-lost record in November HOME regular season

197-159 (+38 more wins, 356 games played, W2) all-time won-lost record against AFC regular season

117-61 (+56 more wins, 178 games played, L1) all-time won-lost record against AFC HOME regular season

32-25 (+7 more wins, 57 games played, W1) all-time won-lost record against AFC East regular season

21-7 (+14 more wins, 28 games played, W2) all-time won-lost record against AFC East HOME regular season

The Ravens are at or above a .500 winning percentage for TWELVE of the 12 categories above. The Ravens have a winning streak for ELEVEN of the 12 categories above. The Ravens have a combined winning and losing streak for the 12 categories above of W21.

Jets 2-10 (-8 more wins, 12 games played, L2) all-time won-lost record against Ravens

Jets 0-6 (-6 more wins, 6 games played, L6) all-time won-lost record against Ravens AWAY

The Jets have never played against the Ravens on November 13th all-time.

The Jets have never played against the Ravens AWAY on November 13th all-time.

The Jets 2-8 (-6 more wins, 10 games played, L1) against the Ravens on Thursdays all-time REGULAR SEASON.

The Jets 0-5 (-5 more wins, 5 games played, L5) against the Ravens on Thursdays AWAY all-time REGULAR SEASON.

Jets 1-2 (-1 more wins, 3 games played, L2) against Ravens on Thursdays in November

Jets 0-1 (-1 more wins, 1 games played, L1) against Ravens AWAY on Thursdays in November

Jets 1-2 (-1 more wins, 3 games played, L2) against Ravens all-time won-lost record in November

Jets 0-1 (-1 more wins, 1 games played, L1) against Ravens all-time won-lost record in November AWAY.

The Jets have never played against the Ravens all-time in Week 12, according to Statmuse.com.

The Jets have never played against the Ravens all-time AWAY in Week 12, according to Statmuse.com.

The Jets against the Ravens have a winning percentage at or above .500 for ZERO of the above twelve data points. The Jets against the Ravens are currently on a winning streak for ZERO of the 12 data points listed above. The Jets have a combined winning and losing streak against the Ravens of L20 based on all of the criteria after the 12 points criteria for each team.

All-time won-lost records for the quarterbacks

Justin Fields (NYJ):

19-40 (-21 more wins, 59 games played, L1) regular season

19-41 (-22 more wins, 60 games played, L1) regular season and postseason

9-21 (-12 more wins, 30 games played, L1) regular season AWAY

9-22 (-13 more wins, 31 games played, L1) regular season and postseason AWAY

2-7 (-5 more wins, 9 games played, L1) regular season with Jets

1-2 (-1 more wins, 3 games played, L1) regular season AWAY with Jets

1-1 (+0 more wins, 2 games played, W1) against Ravens

Lamar Jackson (BAL):

78-32 (+46 more wins, 110 games played, W3) regular season

81-37 (+44 more wins, 118 games played, W3) regular season and postseason

39-14 (+25 more wins, 53 games played, L1) regular season home

41-17 (+24 more wins, 58 games played, L1) regular season and postseason HOME

2-0 (+2 more wins, 2 games played, W2) against Jets

Not an OFFICIAL prediction yet!:

Likely prediction to win: Baltimore Ravens

Likely prediction to lose: New York Jets

Results:

New England Patriots at Cincinnati Bengals

Patriots 554-448-9 (+106 more wins, 1,011 games played, W8) all-time won-lost record REGULAR SEASON

Patriots 246-257-3 (-11 more wins, 506 games played, W5) all-time won-lost record REGULAR SEASON AWAY

Patriots 591-470-9 (+121 more wins, 1,070 games played, W8) all-time won-lost record REGULAR SEASON and POSTSEASON (I think Statmuse screwed this stat up in Week 11, unless I messed it up!)

Patriots 258-270-3 (-12 more wins, 531 games played, W5) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Patriots have a winning and losing streak of W26 for the four categories above. The Patriots are 2-0 this season AT LEAST when it is W20 or higher!

Stats updated/corrected on Monday, November 17th, 2025, after most of the regular season Week 10 games in the 2025-26 season

Patriots 10-2 (+8 more wins, 12 games played, W4) on November 23rd all-time won-lost record

Patriots 2-2 (+0 more wins, 4 games played, W2) all-time won-lost record on November 23rd AWAY

Patriots 474-380-6 (+94 more wins, 860 games played, W7) all-time won-lost record REGULAR SEASON on Sundays

Patriots 213-217-2 (-4 more wins, 432 games played, W5) all-time won-lost record REGULAR SEASON on Sundays AWAY

Patriots 123-102-3 (+21 more wins, 228 games played, W2) all-time won-lost record REGULAR SEASON on Sundays in November

Patriots 58-55-1 (+3 more wins, 114 games played, W1) all-time won-lost record REGULAR SEASON on Sundays in November AWAY

Patriots 144-114-4 (+30 more wins, 262 games played, W3) all-time won-lost record REGULAR SEASON in November

Patriots 65-62-2 (+3 more wins, 129 games played, W1) all-time won-lost record REGULAR SEASON in November AWAY

Patriots 378-283 (+95 more wins, 661 games played, W4) against the AFC all-time in the regular season

Patriots 161-169 (-8 more wins, 330 games played, W3) against the AFC AWAY all-time in the regular season

Patriots 35-11 (+24 more wins, 46 games played, W1) against the AFC North all-time in the regular season

Patriots 15-7 (+8 more wins, 22 games played, W5) against the AFC North AWAY all-time in the regular season

The Patriots have a winning percentage at or above .500 for TEN of the above twelve data points. The Patriots are currently on a winning streak for TWELVE of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W38.

Summary of the summary:

Winning percentage: Seven or higher: 3 wins-0 losses this season at least

Winning streak: Six or higher 3-0

L3 or higher: 3-0

Cincinnati Bengals:

406-486-5 (-80 more wins, 897 games played, L3) all-time won-lost record REGULAR SEASON

244-201-3 (-+43 more wins, 448 games played, L2) all-time won-lost record REGULAR SEASON HOME

416-502-5 (-86 more wins, 923 games played, L3) all-time won-lost record REGULAR SEASON and POSTSEASON

251-208-3 (+43 more wins, 462 games played, L2) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Bengals have a combined winning and losing streak of L10 for the four categories above!

4-3 (+1 more wins, 7 games played, W4) all-time won-lost record on November 23rd

2-0 (+2 more wins, 2 games played, W2) all-time won-lost record on November 23rd HOME

372-439-5 (-67 more wins, 816 games played, L6) all-time won-lost record on Sundays regular season

220-190-3 (+30 more wins, 413 games played, L3) all-time won-lost record on Sundays HOME regular season

102-111-2 (-9 more wins, 215 games played, L3) all-time won-lost record on Sundays in November regular season

58-54-1 (+4 more wins, 113 games played, L1) all-time won-lost record on Sundays in November HOME regular season

106-123-2 (-17 more wins, 231 games played, L4) all-time won-lost record in November regular season

62-58-1 (+4 more wins, 121 games played, L1) all-time won-lost record in November HOME regular season

290-367 (-77 more wins, 657 games played, L2) all-time won-lost record against AFC regular season

174-154 (+20 more wins, 328 games played, L1) all-time won-lost record against AFC HOME regular season

48-73 (-25 more wins, 121 games played, L2) all-time won-lost record against AFC East regular season

29-32 (-3 more wins, 61 games played, L2) all-time won-lost record against AFC East HOME regular season

The Bengals are at or above a .500 winning percentage for SIX of the 12 categories above. The Bengals have a winning streak for TWO of the 12 categories above. The Bengals have a combined winning and losing streak for the 12 categories above of L19.

Patriots 18-10 (+8 more wins, 28 games played, W1) all-time won-lost record against Bengals

Patriots 8-7 (+1 more wins, 15 games played, W2) all-time won-lost record against Bengals AWAY

The Patriots have never played against the Bengals on November 23rd all-time.

The Patriots have never played against the Bengals AWAY on November 23rd all-time.

The Patriots 17-9 (+8 more wins, 26 games played, W4) against the Bengals on Sundays all-time REGULAR SEASON.

The Patriots 7-7 (+0 more wins, 14 games played, W2) against the Bengals on Sundays AWAY all-time REGULAR SEASON.

Patriots 2-0 (+2 more wins, 2 games played, W2) against Bengals on Sundays in November

Patriots 1-0 (+1 more wins, 1 games played, W1) against Bengals AWAY on Sundays in November

Patriots 2-0 (+2 more wins, 2 games played, W2) against Bengals all-time won-lost record in November

Patriots 1-0 (+1 more wins, 1 games played, W1) against Bengals all-time won-lost record in November AWAY.

The Patriots have never played against the Bengals all-time in Week 11, according to Statmuse.com.

The Patriots have never played against the Bengals all-time AWAY in Week 11, according to Statmuse.com.

The Patriots against the Bengals have a winning percentage at or above .500 for EIGHT of the above twelve data points. The Patriots against the Bengals are currently on a winning streak for EIGHT of the 12 data points listed above. The Patriots have a combined winning and losing streak against the Bengals of W15 based on all of the criteria after the 12 points criteria for each team.

All-time won-lost records for the quarterbacks

Drake Maye (NE):

12-12 (+0 more wins, 24 games played, W8) regular season

12-12 (+0 more wins, 24 games played, W8) regular season and postseason

6-6 (+0 more wins, 12 games played, W4) regular season home

Joe Flacco (CIN):

108-97 (+11 more wins, 205 games played) regular season

118-103 (+15 more wins, 221 games played) regular season and postseason

68-35 (+33 more wins, 103 games played, L2) regular season HOME

70-35 (+35 more wins, 105 games played, L2) regular season and postseason HOME

1-4 (-3 more wins, 5 games played, L3) regular season with Bengals

1-2 (-1 more wins, 3 games played, L2) regular season HOME with Bengals

1-5 (-4 more wins, 6 games played, L3) regular season against Patriots

3-7 (-4 more wins, 10 games played, L4) regular season and postseason against Patriots

Not an OFFICIAL prediction yet!:

Likely prediction to win: New England Patriots

Likely prediction to lose: Cincinnati Bengals

Results:

Monday, November 24th, 2025

Monday Night Football, ESPN, 8:15 p.m. Eastern Time

Carolina Panthers at San Francisco 49ers

Panthers 225-269-1 (-44 more wins, 495 games played, W1) all-time won-lost record REGULAR SEASON

Panthers 100-147-1 (-47 more wins, 248 games played, W3) all-time won-lost record REGULAR SEASON AWAY

Panthers 234-277-1 (-43 more wins, 512 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

Panthers 104-153-1 (-49 more wins, 258 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Panthers have a winning and losing streak of W8 for the four categories above.

Carolina Panthers all-time won-lost record updated before game on Monday, November 24th, 2025!:

2-3 (-1 more wins, 5 games played, L2) on November 24th regular season

2-1 (+1 more wins, 3 games played, L1) on November 24th regular season AWAY

10-8 (+2 more wins, 18 games played, L2) on Mondays regular season

3-3 (+0 more wins, 6 games played, W1) on Mondays regular season AWAY

6-1 (+5 more wins, 7 games played, W2) on Mondays regular season in November

1-1 (+0 more wins, 2 games played, L1) on Mondays regular season in November AWAY

56-66 (-10 more wins, 122 games played, W1) in November regular season

25-38 (-13 more wins, 63 games played, W2) in November regular season AWAY

166-200 (-34 more wins, 366 games played, W1) against NFC regular season

75-108 (-33 more wins, 183 games played, W2) against NFC AWAY regular season

51-50 (+1 more wins, 101 games played, L1) against NFC West regular season

24-27 (-3 more wins, 51 games played, L2) against NFC West AWAY regular season

The Panthers have a winning percentage at or above .500 for SIX of the above twelve data points. The Panthers are currently on a winning streak for SIX of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W0.

49ers 599-516-14 (+83 more wins, 1,129 games played, W1) all-time won-lost record REGULAR SEASON

49ers 327-228-8 (+99 more wins, 563 games played, L1) all-time won-lost record REGULAR SEASON HOME

49ers 637-540-14 (+97 more wins, 1,191 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

49ers 356-238-8 (+118 more wins, 602 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The 49ers have a winning and losing streak of W0 for the four categories above.

49ers 5-4 (+1 more wins, 9 games played, L1) on November 24th all-time won-lost record

49ers 2-0 (+2 more wins, 2 games played, W2) all-time won-lost record on November 24th HOME

49ers 53-32 (+21 more wins, 85 games played, L1) all-time won-lost record REGULAR SEASON on Mondays

49ers 31-16 (+15 more wins, 47 games played, L1) all-time won-lost record REGULAR SEASON on Mondays HOME

49ers 19-10 (+9 more wins, 29 games played, W2) all-time won-lost record REGULAR SEASON on Mondays in November

49ers 11-6 (+5 more wins, 17 games played, W1) all-time won-lost record REGULAR SEASON on Mondays in November HOME

49ers 149-149-7 (+0 more wins, 305 games played, W1) all-time won-lost record REGULAR SEASON in November

49ers 79-62-3 (+17 more wins, 144 games played, L2) all-time won-lost record REGULAR SEASON in November HOME

49ers 363-287-4 (+76 more wins, 654 games played, W1) against the NFC all-time in the regular season

49ers 193-129-3 (+64 more wins, 325 games played, L1) against the NFC HOME all-time in the regular season

49ers 20-27 (-7 more wins, 47 games played, W1) against the NFC South all-time in the regular season

49ers 12-11 (+1 more wins, 23 games played, W5) against the NFC South HOME all-time in the regular season

The 49ers have a winning percentage at or above .500 for ELEVEN of the above twelve data points. The 49ers are currently on a winning streak for SEVEN of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W7.

Panthers 13-9 (+4 more wins, 22 games played, L2) all-time won-lost record against 49ers

Panthers 7-4 (+3 more wins, 11 games played, L1) all-time won-lost record against 49ers AWAY

The Panthers have never played against the 49ers on November 24th all-time.

The Panthers have never played against the 49ers AWAY on November 24th all-time.

The Panthers 0-1 (-1 more wins, 1 games played, L1) against the 49ers on Mondays all-time REGULAR SEASON.

The Panthers have never played against the 49ers on Mondays AWAY all-time REGULAR SEASON.

Panthers have never played against 49ers on Mondays in November

Panthers have never played against 49ers on Mondays AWAY in November

Panthers 3-3 (+0 more wins, 6 games played, W2) against 49ers all-time won-lost record in November

Panthers 3-2 (+1 more wins, 5 games played, W2) against 49ers all-time won-lost record in November AWAY.

The Panthers 0-1 (-1 more wins, 1 games played, L1) against the 49ers all-time in Week 12, according to Statmuse.com.

The Panthers 0-1 (-1 more wins, 1 games played, L1) against the 49ers all-time AWAY in Week 11, according to Statmuse.com.

The Panthers against the 49ers have a winning percentage at or above .500 for FOUR of the above twelve data points. The Panthers against the 49ers are currently on a winning streak for TWO of the 12 data points listed above. The Panthers have a combined winning and losing streak against the 49ers of L2 based on all of the criteria after the 12 points criteria for each team.

All-time won-lost records for the quarterbacks

Bryce Young (CAR):

12-28 (-16 more wins, 40 games played, W1) regular season

12-28 (-16 more wins, 40 games played, W1) regular season and postseason

4-17 (-13 more wins, 21 games played, W3) regular season AWAY

4-17 (-13 more wins, 21 games played, W3) regular season and postseason AWAY

0-0 (+0 more wins, 0 games played) against 49ers

Brock Purdy (SF):

28-15 (+13 more wins, 43 games played, W1) regular season

13-9 (+4 more wins, 22 games played, L3) regular season HOME

32-17 (+15 more wins, 49 games played, W1) regular season and postseason

17-9 (+8 more wins, 26 games played, L3) regular season and postseason HOME

1-0 (+1 more wins, 1 games played, W1) against Panthers regular season

1-0 (+1 more wins, 1 games played, W1) against Panthers regular season and postseason

Not an OFFICIAL prediction yet!:

Likely prediction to win: San Francisco 49ers

Likely prediction to lose: Carolina Panthers

Results:  

Those are all of my predictions for right now! Be sure to come back to this page for my re-predictions of my NFL original predictions for Regular Season Week 12 (and also to see how many wins and losses I actually get with my original predictions and my re-predictions for Regular Season Week 12) and be sure to come back to this website for my predictions to win and lose for next week (and for every single week after that for the entire 2025-26 National Football League season or until as long as I want to keep making predictions)!

Be sure to follow me on my various social media which you can find on this page for right now. Also, be sure to follow me on Twitter/X @Evan_Troxel. Also, be sure to definitely follow me on Gab @Evan_Troxel as well in case I ever get censored and banned from X and Facebook!

I reserve the right to change my predictions before game time. I also can change my predictions AFTER game time ONLY if I decide BEFORE game time that I want to change my predictions and I just do not have access to the Internet before game time.

LEGAL NOTICE: I DO NOT endorse and I do not encourage people to gamble or bet your own money and other people's money at all! These predictions are not meant to be taken as extremely serious advice for betting and gambling purposes anytime at all in the near future!