NFL 2025-26: Week 16 #2 Regular Season Predictions

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(EDITOR'S NOTE: A lot of information posted here in this story is from statmuse.com, so please go use Statmuse for yourself to find any sports statistics and scores about all of your favorite athletes and teams in every major professional sport and strongly consider giving them your money to use their service for more detailed information if you already really like what you see when you use their services for free!)

(ADDITIONAL NOTE, VERY IMPORTANT!: This post/story is for the Sunday late afternoon, Sunday Night and Monday Night games! Like last week, I guess I will plan on creating a second post/story for the Thursday Night, Sunday morning and Sunday early afternoon games and I will post the link here after I publish that story! So I am forced to split up my story into parts because for some odd reason my post/story is too long! Honestly, I think the real reason is that the computer that I am using is just way too slow! This is my predictions to win and lose for right now in a story/post from my personal website for the Thursday Night, Saturday, Sunday morning and early Sunday afternoon games in regular season Week 16 right here!: https://ogeagleet852.wixsite.com/evantroxel/single-post/nfl-2025-26-week-16-1-regular-season-predictions

By: Evan Troxel

These are my predictions to win and lose for the 2025-26 National Football League season for Regular Season Week 16 from Thursday, December 18th, 2025, through Monday, December 22nd, 2025!

Please follow me on Gab.com at Gab.com/EvanTroxel and on Telegram at t.me/Evan_Troxel for my re-predictions before game time and my FINAL predictions to win and lose all games in REGULAR SEASON Week 15 and in every week of the National Football League all season long if I don't post the FINAL PREDICTIONS right here in this story! Also, be sure to follow me on Gab and Telegram for additional notes in the days leading up to the game!

NFL 2025-26 Regular Season Week 16 Predictions 

There are zero teams on a bye week this week!

Now that we've gotten that out of the way, these are the referee assignments for REGULAR SEASON Week 16 on footballzebras.com when they actually post the link!: https://www.footballzebras.com/2025/12/week-16-referee-assignments-2025/

Thursday, December 18th, 2025

Los Angeles Rams at Seattle Seahawks, 8:15 p.m. Eastern Time (Prime Video)

In Gematria:

Thursday: 116/35/100/46

Thursday Night Football: 257/95/310/112

TNF: 40/13/41/14

The fill in the blank number is the fill in the blank prime number above...!:

Thursday: 641 is the 116th prime!/149/541/199

Thursday Night Football: 1621/499/2053/613

TNF: 173/41/179/43

The Los Angeles Rams all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

Rams 635-609-21 (+26 more wins, 1,265 games played, W2) all-time won-lost record REGULAR SEASON

Rams 285-342-11 (-57 more wins, 638 games played, W1) all-time won-lost record REGULAR SEASON AWAY

Rams 662-638-21 (+24 more wins, 1,321 games played, W2) all-time won-lost record REGULAR SEASON and POSTSEASON

Rams 297-362-11 (-65 more wins, 670 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Rams have a winning and losing streak of W6 for the four categories above.

Rams 2-8 (-6 more wins, 10 games played, L4) on December 18th all-time won-lost record

Rams 2-3 (-1 more wins, 5 games played, L2) on December 18th AWAY

Rams 15-12 (+3 more wins, 27 games played, L1) all-time won-lost record REGULAR SEASON on Thursdays

Rams 7-6 (+1 more wins, 13 games played, W2) all-time won-lost record REGULAR SEASON on Thursdays AWAY

Rams 5-5 (+0 more wins, 10 games played, W4) all-time won-lost record REGULAR SEASON on Thursdays in December

Rams 1-2 (-1 more wins, 3 games played, W1) all-time won-lost record REGULAR SEASON on Thursdays in December AWAY

Rams 146-131-2 (+15 more wins, 279 games played, W10) all-time won-lost record REGULAR SEASON in December

Rams 59-65 (-6 more wins, 124 games played, W5) all-time won-lost record REGULAR SEASON in December AWAY

Rams 329-322-5 (+7 more wins, 656 games played, W2) against the NFC all-time in the regular season

Rams 148-175-3 (-27 more wins, 326 games played, W1) against the NFC AWAY all-time in the regular season

Rams 177-166-3 (+11 more wins, 346 games played, W3) against the NFC West all-time in the regular season

Rams 87-85-1 (+2 more wins, 173 games played, W4) against the NFC West AWAY all-time in the regular season

The Rams have a winning percentage at or above .500 for SEVEN of the above twelve data points. The Rams are currently on a winning streak for NINE of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W25.

The Seattle Seahawks all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

413-376-1 (+37 more wins, 790 games played, W4) all-time won-lost record REGULAR SEASON

238-158 (+80 more wins, 396 games played, W4) all-time won-lost record REGULAR SEASON HOME

430-395-1 (+35 more wins, 826 games played, W4) all-time won-lost record REGULAR SEASON and POSTSEASON

250-162 (+88 more wins, 412 games played, W4) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Seahawks have a combined winning and losing streak of W16 for the four categories above!

6-1 (+5 more wins, 7 games played, W3) all-time won-lost record on December 18th

3-1 (+2 more wins, 4 games played, W1) all-time won-lost record on December 18th HOME

13-10 (+3 more wins, 23 games played, W2) all-time won-lost record on Thursdays regular season

6-5 (+1 more wins, 11 games played, L4) all-time won-lost record on Thursdays HOME regular season

3-2 (+1 more wins, 5 games played, W1) all-time won-lost record on Thursdays in December regular season

2-2 (+0 more wins, 4 games played, L1) all-time won-lost record on Thursdays in December HOME regular season

107-90 (+17 more wins, 197 games played, W3) all-time won-lost record in December regular season

65-40 (+25 more wins, 105 games played, W1) all-time won-lost record in December HOME regular season

212-173-1 (+39 more wins, 386 games played, W2) all-time won-lost record against NFC regular season

114-81 (+33 more wins, 195 games played, W2) all-time won-lost record against NFC HOME regular season

96-73-1 (+23 more wins, 170 games played, L1) all-time won-lost record against NFC West regular season

44-39-1 (+5 more wins, 84 games played, L1) all-time won-lost record against NFC West HOME regular season

The Seahawks are at or above a .500 winning percentage for TWELVE of the 12 categories above. The Seahawks have a winning streak for EIGHT of the 12 categories above. The Seahawks have a combined winning and losing streak for the 12 categories above of W8.

Rams 26-28 (-2 more wins, 54 games played, W1) all-time won-lost record against Seahawks

Rams 10-17 (-7 more wins, 27 games played, W2) all-time won-lost record against Seahawks AWAY

The Rams have never played against the Seahawks on December 18th all-time.

The Rams have never played against the Seahawks AWAY on December 18th all-time.

The Rams 1-2 (-1 more wins, 3 games played, W1) against the Seahawks on Thursdays all-time REGULAR SEASON.

The Rams 1-2 (-1 more wins, 3 games played, W1) against the Seahawks on Thursdays AWAY all-time REGULAR SEASON.

Rams 0-1 (-1 more wins, 1 games played, L1) against Seahawks on Thursdays in December

Rams 0-1 (-1 more wins, 1 games played, L1) against Seahawks on Thursdays AWAY in December

Rams 5-10 (-5 more wins, 15 games played, L1) against Seahawks all-time won-lost record in December

Rams 2-8 (-6 more wins, 10 games played, L1) against Seahawks all-time won-lost record in December AWAY.

The Rams 1-2 (-1 more wins, 3 games played, L1) against the Seahawks all-time in Week 16, according to Statmuse.com.

The Rams 1-2 (-1 more wins, 3 games played, L1) against the Seahawks all-time AWAY in Week 16, according to Statmuse.com.

The Rams against the Seahawks have a winning percentage at or above .500 for ZERO of the above twelve data points. The Rams against the Seahawks are currently on a winning streak for FOUR of the 12 data points listed above. The Rams have a combined winning and losing streak against the Seahawks of L1 based on all of the criteria after the 12 points criteria for each team.

Predicted on Monday, December 15th, 2025, at 5:05 p.m. Eastern Time

Prediction to win: Los Angeles Rams

Prediction to lose: Seattle Seahawks

Results:

Saturday, December 20th, 2025

Philadelphia Eagles at Washington Commanders, 5:00 p.m. Eastern Time (FOX)

The Philadelphia Eagles all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

647-644-27 (+3 more wins, 1,318 games played, W1) all-time won-lost record REGULAR SEASON

285-355-13 (-70 more wins, 653 games played, L2) all-time won-lost record REGULAR SEASON AWAY

676-670-27 (+6 more wins, 1,373 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

293-369-13 (-77 more wins, 676 games played, L2) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Eagles have a combined winning and losing streak of L2 for the four categories above!

5-4 (+1 more wins, 9 games played, L3) all-time won-lost record on December 20th

1-3 -2 more wins, 4 games played, L3) all-time won-lost record on December 20th AWAY

17-25 (-8 more wins, 42 games played, L4) all-time won-lost record on Saturdays regular season

7-11 (-4 more wins, 18 games played, L2) all-time won-lost record on Saturdays AWAY regular season

6-11 (-5 more wins, 17 games played, L3) on Saturdays in December regular season

6-7 (-1 more wins, 13 games played, L2) on Saturdays in December AWAY regular season

149-132-4 (+17 more wins, 285 games played, W1) all-time won-lost record in December regular season

64-72-3 (-8 more wins, 139 games played, L2) all-time won-lost record in December AWAY regular season

342-313-6 (+29 more wins, 661 games played, L2) all-time won-lost record against NFC regular season

159-167-3 (-8 more wins, 329 games played, L1) all-time won-lost record against NFC AWAY regular season

200-192-4 (+8 more wins, 396 games played, L1) all-time won-lost record against NFC East regular season

93-103-2 (-10 more wins, 198 games played, L3) all-time won-lost record against NFC East AWAY regular season

The Eagles are at or above a .500 winning percentage for FOUR of the 12 categories above. The Eagles have a winning streak for ONE of the 12 categories above. The Eagles have a combined winning and losing streak for the 12 categories above of L25.

The Washington Commanders all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

Commanders 645-658-29 (-13 more wins, 1,332 games played, W1) all-time won-lost record REGULAR SEASON

Commanders 366-297-11 (+69 more wins, 674 games played, L4) all-time won-lost record REGULAR SEASON HOME

Commanders 670-679-29 (-9 more wins, 1,378 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

Commanders 380-304-11 (+76 more wins, 695 games played, L4) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Commanders have a winning and losing streak of L6 for the four categories above.

Commanders 4-3 (+1 more wins, 7 games played, L1) on December 20th all-time won-lost record

Commanders 3-1 (+2 more wins, 4 games played, L1) all-time won-lost record on December 20th HOME

Commanders 17-19 (-2 more wins, 36 games played, L2) all-time won-lost record REGULAR SEASON on Saturdays

Commanders 6-6 (+0 more wins, 12 games played, W1) all-time won-lost record REGULAR SEASON on Saturdays HOME

Commanders 15-16 (-1 more wins, 31 games played, L2) all-time won-lost record REGULAR SEASON on Saturdays in December

Commanders 6-6 (+0 more wins, 12 games played, W1) all-time won-lost record REGULAR SEASON on Saturdays in December HOME

Commanders 141-139-5 (+2 more wins, 285 games played, W1) all-time won-lost record REGULAR SEASON in December

Commanders 71-74-2 (-3 more wins, 147 games played, W3) all-time won-lost record REGULAR SEASON in December HOME

Commanders 341-318-3 (+23 more wins, 662 games played, W1) against the NFC all-time in the regular season

Commanders 190-139-2 (+51 more wins, 331 games played, L3) against the NFC HOME all-time in the regular season

Commanders 189-204-3 (-15 more wins, 396 games played, W1) against the NFC East all-time in the regular season

Commanders 107-89-2 (+18 more wins, 198 games played, W2) against the NFC East HOME all-time in the regular season

The Commanders have a winning percentage at or above .500 for EIGHT of the above twelve data points. The Commanders are currently on a winning streak for SEVEN of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W1.

Predicted on Tuesday, December 16th, 2025, at 7:47 p.m. Eastern Time

Prediction to win: Washington Commanders

Prediction to lose: Philadelphia Eagles

Results:

Saturday, December 20th, 2025

Green Bay Packers at Chicago Bears, 8:20 p.m. Eastern Time (FOX)

The Green Bay Packers all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

819-608-39 (+211 more wins, 1,466 games played, L1) all-time won-lost record REGULAR SEASON

342-367-19 (-25 more wins, 728 games played, L1) all-time won-lost record REGULAR SEASON AWAY

856-635-39 (+221 more wins, 1,530 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON

356-387-19 (-31 more wins, 762 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Packers have a combined winning and losing streak of L4 for the four categories above!

4-5 (-1 more wins, 9 games played, W1) all-time won-lost record on December 20th

1-5 (-4 more wins, 6 games played, W1) all-time won-lost record on December 20th AWAY

19-13 (+6 more wins, 32 games played, W2) all-time won-lost record on Saturdays regular season

13-8 (+5 more wins, 21 games played, W3) all-time won-lost record on Saturdays AWAY regular season

14-9 (+5 more wins, 23 games played, W2) all-time won-lost record on Saturdays in December regular season

10-5 (+5 more wins, 15 games played, W3) all-time won-lost record on Saturdays in December AWAY regular season

170-112-9 (+58 more wins, 291 games played, L1) all-time won-lost record in December regular season

92-87-8 (+5 more wins, 187 games played, L2) all-time won-lost record in December AWAY regular season

368-284-8 (+84 more wins, 660 games played, W4) all-time won-lost record against NFC regular season

149-177-3 (-28 more wins, 329 games played, W3) all-time won-lost record against NFC AWAY regular season

93-47-2 (+46 more wins, 142 games played, W4) all-time won-lost record against NFC North regular season

44-26 (+18 more wins, 70 games played, W1) all-time won-lost record against NFC North regular season AWAY

The Packers are at or above a .500 winning percentage for NINE of the 12 categories above. The Packers have a winning streak for TEN of the 12 categories above. The Packers have a combined winning and losing streak for the 12 categories above of W21.

The Chicago Bears all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

808-650-42 (+158 more wins, 1,500 games played, W1) all-time won-lost record REGULAR SEASON

466-278-24 (+188 more wins, 768 games played, W5) all-time won-lost record REGULAR SEASON HOME

825-670-42 (+155 more wins, 1,537 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

478-288-24 (+190 more wins, 790 games played, W5) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Bears have a combined winning and losing streak of W12 for the four categories above!

6-5 (+3 more wins, 15 games played, L1) all-time won-lost record on December 20th

2-2 (-1 more wins, 9 games played, L1) all-time won-lost record on December 20th HOME

10-15-1 (+1 more wins, 3 games played, L1) all-time won-lost record on Saturdays regular season

4-8-1 (-1 more wins, 1 games played, L1) all-time won-lost record on Saturdays HOME regular season

6-12-1 (-6 more wins, 19 games played, L3) all-time won-lost record on Saturdays in December regular season

3-8-1 (-5 more wins, 12 games played, L2) all-time won-lost record on Saturdays in December HOME regular season

155-149-9 (+6 more wins, 313 games played, W1) all-time won-lost record in December regular season

95-70-8 (+25 more wins, 173 games played, W1) all-time won-lost record in December HOME regular season

316-341-1 (-25 more wins, 658 games played, L1) all-time won-lost record against NFC regular season

184-143-1 (+41 more wins, 328 games played, W3) all-time won-lost record against NFC HOME regular season

59-83 (-24 more wins, 142 games played, L1) all-time won-lost record against NFC North regular season

34-36 (-2 more wins, 70 games played, L4) all-time won-lost record against NFC North HOME regular season

The Bears are at or above a .500 winning percentage for FIVE of the 12 categories above. The Bears have a winning streak for THREE of the 12 categories above. The Bears have a combined winning and losing streak for the 12 categories above of L13.

Predicted on Wednesday, December 17th, 2025, at 9:24 p.m. Eastern Time

Prediction to win: Chicago Bears

Prediction to lose: Green Bay Packers

Results:

Sunday, December 21st, 2025

Buffalo Bills at Cleveland Browns, 1:00 p.m. Eastern Time (CBS)

Buffalo Bills all-time won-lost records before regular season Week 16!:

Bills 496-509-8 (-13 more wins, 1,013 games played, W3) all-time won-lost record REGULAR SEASON

Bills 209-292-4 (-83 more wins, 505 games played, W2) all-time won-lost record REGULAR SEASON AWAY

Bills 517-531-8 (-14 more wins, 1,056 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON

Bills 213-307-4 (-94 more wins, 524 games played, W2) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Bills have a winning and losing streak of W10 for the four categories above.

Bills 2-4 (-3 more wins, 6 games played, L2) on December 21st all-time won-lost record

Bills 2-3 (-1 more wins, 5 games played, L2) all-time won-lost record on December 21st AWAY

Bills 434-444-5 (-10 more wins, 883 games played, W4) all-time won-lost record REGULAR SEASON on Sundays

Bills 175-252-2 (-77 more wins, 429 games played, W2) all-time won-lost record REGULAR SEASON on Sundays AWAY

Bills 91-111-1 (-20 more wins, 203 games played, W5) all-time won-lost record REGULAR SEASON on Sundays in December

Bills 44-72 (-28 more wins, 116 games played, W2) all-time won-lost record REGULAR SEASON on Sundays in December AWAY

Bills 107-129-1 (-22 more wins, 237 games played, W5) all-time won-lost record REGULAR SEASON in December

Bills 57-84 (-27 more wins, 141 games played, W2) all-time won-lost record REGULAR SEASON in December AWAY

Bills 318-344-1 (-26 more wins, 603 games played, W3) against the AFC all-time in the regular season

Bills 133-196-1 (-63 more wins, 330 games played, W2) against the AFC AWAY all-time in the regular season

Bills 23-23 (+0 more wins, 46 games played, W3) against the AFC North all-time in the regular season

Bills 8-14 (-6 more wins, 22 games played, W1) against the AFC North AWAY all-time in the regular season

The Bills have a winning percentage at or above .500 for ONE of the above twelve data points. The Bills are currently on a winning streak for TEN of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W25.

The Cleveland Browns all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

518-555-11 (-37 more wins, 1,084 games played, L3) all-time won-lost record REGULAR SEASON

290-245-6 (+45 more wins, 541 games played, L3) all-time won-lost record REGULAR SEASON HOME

530-577-11 (-47 more wins, 1,118 games played, WL3) all-time won-lost record REGULAR SEASON and POSTSEASON

299-251-6 (+48 more wins, 556 games played, L3) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Browns have a combined winning and losing streak of L12 for the four categories above!

3-6 (-3 more wins, 9 games played, L3) all-time won-lost record on December 21st

2-2 (+0 more wins, 4 games played, L2) all-time won-lost record on December 21st HOME

465-510-11 (-44 more wins, 986 games played, L3) all-time won-lost record on Sundays regular season

257-226-6 (+31 more wins, 489 games played, L3) all-time won-lost record on Sundays HOME regular season

90-131-2 (-41 more wins, 223 games played, L6) all-time won-lost record on Sundays in December regular season

46-43 (+3 more wins, 89 games played, L3) all-time won-lost record on Sundays in December HOME regular season

104-149-2 (-45 more wins, 255 games played, L7) all-time won-lost record in December regular season

51-50 (+1 more wins, 101 games played, L3) all-time won-lost record in December HOME regular season

253-366-4 (-113 more wins, 623 games played, L1) all-time won-lost record against AFC regular season

106-207-1 (-101 more wins, 314 games played, L1) all-time won-lost record against AFC HOME regular season

60-57 (+3 more wins, 117 games played, L2) all-time won-lost record against AFC East regular season

37-27 (+10 more wins, 64 games played, W1) all-time won-lost record against AFC East HOME regular season

The Browns are at or above a .500 winning percentage for SIX of the 12 categories above. The Browns have a winning streak for ONE of the 12 categories above. The Browns have a combined winning and losing streak for the 12 categories above of L33.

Predicted on Wednesday, December 17th, 2025, at 9:24 p.m. Eastern Time

Prediction to win: Buffalo Bills

Prediction to lose: Cleveland Browns

Results:

Sunday, December 21st, 2025

Los Angeles Chargers at Dallas Cowboys, 1:00 p.m. Eastern Time (FOX)

Predicted on Wednesday, December 17th, 2025, at 9:25 p.m. Eastern Time

Prediction to win: Dallas Cowboys

Prediction to lose: Los Angeles Chargers

Results:

Sunday, December 21st, 2025

Kansas City Chiefs at Tennessee Titans, 1:00 p.m. Eastern Time (CBS)

Predicted on Wednesday, December 17th, 2025, at 9:27 p.m. Eastern Time

Prediction to win: Kansas City Chiefs

Prediction to lose: Tennessee Titans

Results:

Sunday, December 21st, 2025

Cincinnati Bengals at Miami Dolphins, 1:00 p.m. Eastern Time (CBS)

Predicted on Wednesday, December 17th, 2025, at 9:27 p.m. Eastern Time

Prediction to win: Cincinnati Bengals

Prediction to lose: Miami Dolphins

Results:

Sunday, December 21st, 2025

New York Jets at New Orleans Saints, 1:00 p.m. Eastern Time (CBS)

Predicted on Wednesday, December 17th, 2025, at 9:28 p.m. Eastern Time

Prediction to win: New Orleans Saints

Prediction to lose: New York Jets

Results:

Sunday, December 21st, 2025

Minnesota Vikings at New York Giants, 1:00 p.m. Eastern Time (FOX)

Predicted on Wednesday, December 17th, 2025, at 9:52 p.m. Eastern Time

Prediction to win: New York Giants

Prediction to lose: Minnesota Vikings

Results:

Sunday, December 21st, 2025

Tampa Bay Buccaneers at Carolina Panthers, 1:00 p.m. Eastern Time (FOX)

Predicted on Wednesday, December 17th, 2025, at 9:31 p.m. Eastern Time

Prediction to win: Tampa Bay Buccaneers

Prediction to lose: Carolina Panthers

Results:

Sunday, December 21st, 2025

Jacksonville Jaguars at Denver Broncos, 4:05 p.m. Eastern Time (FOX)

The Jacksonville Jaguars all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

212-286 (-74 more wins, 498 games played, W5) all-time won-lost record REGULAR SEASON

84-164 (-80 more wins, 248 games played, W2) all-time won-lost record REGULAR SEASON AWAY

220-294 (-74 more wins, 514 games played, W5) all-time won-lost record REGULAR SEASON and POSTSEASON

88-171 (-83 more wins, 259 games played, W2) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Jaguars have a combined winning and losing streak of W14 for the four categories above!

2-0 (+2 more wins, 2 games played, W2) all-time won-lost record on December 21st

1-0 (+1 more wins, 1 games played, W1) on December 21st AWAY

193-266 (-73 more wins, 459 games played, W5) all-time won-lost record on Sundays regular season

80-154 (-74 more wins, 234 games played, W2) all-time won-lost record on Sundays AWAY regular season

47-68 (-21 more wins, 115 games played, W3) all-time won-lost record on Sundays in December regular season

18-38 (-20 more wins, 56 games played, L1) all-time won-lost record on Sundays in December AWAY regular season

55-78 (-23 more wins, 133 games played, W3) all-time won-lost record in December regular season

20-43 (-23 more wins, 63 games played, L1) all-time won-lost record in December AWAY regular season

166-204 (-38 more wins, 370 games played, W4) all-time won-lost record against AFC regular season

68-116 (-48 more wins, 184 games played, W1) all-time won-lost record against AFC AWAY regular season

26-33 (-7 more wins, 59 games played, W3) all-time won-lost record against AFC West regular season

10-18 (-8 more wins, 28 games played, W1) all-time won-lost record against AFC West AWAY regular season

The Jaguars are at or above a .500 winning percentage for TWO of the 12 categories above. The Jaguars have a winning streak for TEN of the 12 categories above. The Jaguars have a combined winning and losing streak for the 12 categories above of W23.

The Denver Broncos all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

Broncos 530-474-10 (+56 more wins, 1,014 games played, W11) all-time won-lost record REGULAR SEASON

Broncos 318-183-7 (+135 more wins, 508 games played, W12) all-time won-lost record REGULAR SEASON HOME

Broncos 553-494-10 (+59 more wins, 1,057 games played, W11) all-time won-lost record REGULAR SEASON and POSTSEASON

Broncos 337-192-7 (+145 more wins, 536 games played, W12) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Broncos have a winning and losing streak of W46 for the four categories above.

Broncos 3-2 (+1 more wins, 5 games played, L1) on December 21st all-time won-lost record

Broncos 1-1 (+0 more wins, 2 games played, L1) on December 21st at HOME all-time won-lost record

Broncos 460-386-8 (+74 more wins, 854 games played, W9) on Sundays REGULAR SEASON all-time

Broncos 278-157-6 (+121 more wins, 441 games played, W9) on Sundays REGULAR SEASON HOME all-time

Broncos 90-104-4 (-14 more wins, 195 games played, W4) all-time won-lost record REGULAR SEASON on Sundays in December

Broncos 60-30-1 (+30 more wins, 91 games played, W3) all-time won-lost record REGULAR SEASON on Sundays in December at HOME

Broncos 108-131-1 (-23 more wins, 240 games played, W2) all-time won-lost record REGULAR SEASON in December

Broncos 68-36-1 (+32 more wins, 105 games played, W4) all-time won-lost record REGULAR SEASON in December HOME

Broncos 366-285-4 (+81 more wins, 655 games played, W6) all-time won-lost record REGULAR SEASON against AFC

Broncos 217-106-4 (+111 more wins, 327 games played, W7) all-time won-lost record REGULAR SEASON against AFC HOME

Broncos 24-23 (+1 more wins, 47 games played, W1) all-time won-lost record REGULAR SEASON against AFC South

Broncos 13-10 (+3 more wins, 23 games played, W2) all-time won-lost record REGULAR SEASON against AFC South HOME

The Broncos have a winning percentage at or above .500 for TEN of the above twelve data points. The Broncos are currently on a winning streak for TEN of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W45.

Predicted on Wednesday, December 17th, 2025, at 9:34 p.m. Eastern Time

Prediction to win: Denver Broncos

Prediction to lose: Jacksonville Jaguars

Results:

Sunday, December 21st, 2025

Atlanta Falcons at Arizona Cardinals, 4:05 p.m. Eastern Time (FOX)

The Atlanta Falcons all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

404-520-6 (-116 more wins, 930 games played, W1) all-time won-lost record REGULAR SEASON

170-291-4 (-121 more wins, 465 games played, W3) all-time won-lost record REGULAR SEASON AWAY

414-534-6 (-120 more wins, 954 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

174-300-4 (-126 more wins, 778 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Falcons have a combined winning and losing streak of W8 for the four categories above!

4-4 (+0 more wins, 8 games played, W2) all-time won-lost record on December 21st

3-3 (+0 more wins, 6 games played, W2) all-time won-lost record on December 21st AWAY

368-475-6 (-107 more wins, 849 games played, L2) all-time won-lost record on Sundays regular season

156-263-4 (-107 more wins, 423 games played, L1) all-time won-lost record on Sundays AWAY regular season

84-113 (-29 more wins, 197 games played, L2) all-time won-lost record on Sundays in December regular season

35-64 (-29 more wins, 99 games played, L4) all-time won-lost record on Sundays in December AWAY regular season

96-128 (-32 more wins, 224 games played, W1) all-time won-lost record in December regular season

41-74 (-33 more wins, 115 games played, W1) all-time won-lost record in December AWAY regular season

303-349-4 (-46 more wins, 656 games played, W1) all-time won-lost record against NFC regular season

127-198-3 (-71 more wins, 328 games played, W2) all-time won-lost record against NFC AWAY regular season

117-130-3 (-13 more wins, 250 games played, L4) all-time won-lost record against NFC West regular season

45078-2 (-33 more wins, 125 games played, L2) all-time won-lost record against NFC West AWAY regular season

The Falcons are at or above a .500 winning percentage for TWO of the 12 categories above. The Falcons have a winning streak for SIX of the 12 categories above. The Falcons have a combined winning and losing streak for the 12 categories above of L6.

The Arizona Cardinals all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

596-823-41 (-227 more wins, 1,460 games played, L6) all-time won-lost record REGULAR SEASON

340-356-23 (-16 more wins, 719 games played, L6) all-time won-lost record REGULAR SEASON HOME

603-833-41 (-230 more wins, 1,477 games played, L6) all-time won-lost record REGULAR SEASON and POSTSEASON

345-357-23 (-12 more wins, 725 games played, L6) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Cardinals have a combined winning and losing streak of L24 for the four categories above!

3-8 (-5 more wins, 11 games played, L4) all-time won-lost record on December 21st

2-4 (-2 more wins, 6 games played, L2) all-time won-lost record on December 21st HOME

542-739-36 (-197 more wins, 1,317 games played, L10) all-time won-lost record on Sundays regular season

310-316-21 (-6 more wins, 647 games played, L5) all-time won-lost record on Sundays HOME regular season

108-146-6 (-38 more wins, 260 games played, L3) all-time won-lost record on Sundays in December regular season

66-68-3 (-2 more wins, 137 games played, L1) all-time won-lost record on Sundays in December HOME regular season

119-167-6 (-48 more wins, 292 games played, L4) all-time won-lost record in December regular season

74-80-3 (-6 more wins, 157 games played, L1) all-time won-lost record in December HOME regular season

281-386-6 (-105 more wins, 673 games played, L4) all-time won-lost record against NFC regular season

163-168-4 (-5 more wins, 335 games played, L4) all-time won-lost record against NFC HOME regular season

18-29 (-11 more wins, 47 games played, L1) all-time won-lost record against NFC South regular season

14-9 (+5 more wins, 23 games played, W2) all-time won-lost record against NFC South HOME regular season

The Cardinals are at or above a .500 winning percentage for ONE of the 12 categories above. The Cardinals have a winning streak for ONE of the 12 categories above. The Cardinals have a combined winning and losing streak for the 12 categories above of L37.

Predicted on Wednesday, December 17th, 2025, at 9:37 p.m. Eastern Time

Prediction to win: Arizona Cardinals

Prediction to lose: Atlanta Falcons

Results:

Sunday, December 21st, 2025

Pittsburgh Steelers at Detroit Lions, 4:25 p.m. Eastern Time (CBS)

The Pittsburgh Steelers all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

689-591-22 (+98 more wins, 1,302 games played, W2) all-time won-lost record REGULAR SEASON

288-352-12 (-64 more wins, 652 games played, W1) all-time won-lost record REGULAR SEASON AWAY

725-620-22 (+105 more wins, 1,367 games played, W2) all-time won-lost record REGULAR SEASON and POSTSEASON

300-368-12 (-68 more wins, 680 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Steelers have a combined winning and losing streak of W6 for the four categories above!

2-8 (-6 more wins, 10 games played, L2) all-time won-lost record on December 21st

0-6 (-6 more wins, 6 games played, L6) all-time won-lost record on December 21st AWAY

580-504-21 (+76 more wins, 1,104 games played, W1) all-time won-lost record on Sundays regular season

244-293-12 (-49 more wins, 549 games played, W1) all-time won-lost record on Sundays AWAY regular season

125-102-2 (+23 more wins, 229 games played, W1) all-time won-lost record on Sundays in December regular season

52-63-1 (-11 more wins, 116 games played, W1) all-time won-lost record on Sundays in December AWAY regular season

153-124-2 (+29 more wins, 279 games played, W2) all-time won-lost record in December regular season

65-81-1 (-16 more wins, 147 games played, W1) all-time won-lost record in December AWAY regular season

129-81-2 (+48 more wins, 212 games played, L2) all-time won-lost record against NFC regular season

53-51 (+2 more wins, 104 games played, L2) all-time won-lost record against NFC AWAY regular season

15-8-1 (+7 more wins, 24 games played, L2) all-time won-lost record against NFC North regular season

5-6 (-1 more wins, 11 games played, L3) all-time won-lost record against NFC North AWAY regular season

The Steelers are at or above a .500 winning percentage for SIX of the 12 categories above. The Steelers have a winning streak for SIX of the 12 categories above. The Steelers have a combined winning and losing streak for the 12 categories above of L10.

The Detroit Lions all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

614-715-34 (-101 more wins, 1,363 games played, L1) all-time won-lost record REGULAR SEASON

374-304-14 (+70 more wins, 692 games played, W1) all-time won-lost record REGULAR SEASON HOME

623-730-34 (-107 more wins, 1,387 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON

381-306-14 (+75 more wins, 701 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Lions have a combined winning and losing streak of W0 for the four categories above!

6-4 (+2 more wins, 10 games played, W2) all-time won-lost record on December 21st

3-3 (+0 more wins, 6 games played, L1) all-time won-lost record on December 21st HOME

508-624-29 (-116 more wins, 1,161 games played, L1) all-time won-lost record on Sundays regular season

293-236-12 (+57 more wins, 541 games played, W1) all-time won-lost record on Sundays HOME regular season

100-132-4 (-32 more wins, 236 games played, L1) all-time won-lost record on Sundays in December regular season

58-53-2 (+5 more wins, 113 games played, L1) all-time won-lost record on Sundays in December HOME regular season

118-152-4 (-34 more wins, 274 games played, L1) all-time won-lost record in December regular season

69-65-2 (+4 more wins, 136 games played, W1) all-time won-lost record in December HOME regular season

85-123-2 (-38 more wins, 210 games played, L1) all-time won-lost record against AFC regular season

52-52 (+0 more wins, 104 games played, W1) all-time won-lost record against AFC HOME regular season

8-15-1 (-31 more wins, 141 games played, W3) all-time won-lost record against AFC North regular season

4-7 (-3 more wins, 11 games played, W1) all-time won-lost record against AFC North HOME regular season

The Lions are at or above a .500 winning percentage for SIX of the 12 categories above. The Lions have a winning streak for SIX of the 12 categories above. The Lions have a combined winning and losing streak for the 12 categories above of W3.

Steelers 17-14-2 (+3 more wins, 33 games played, Tie 1 and W5 before that) all-time won-lost record against Lions

Steelers 6-12 (-6 more wins, 18 games played, W2) all-time won-lost record against Lions AWAY

The Steelers have never played against the Lions on December 21st all-time.

The Steelers have never played against the Lions AWAY on December 21st all-time.

The Steelers 16-11-2 (+5 more wins, 29 games played, Tie 1 and W13 before that) against the Lions on Sundays all-time REGULAR SEASON.

The Steelers 6-9 (-3 more wins, 15 games played, W4) against the Lions on Sundays AWAY all-time REGULAR SEASON.

Steelers 3-1 (+2 more wins, 4 games played, W3) against Lions on Sundays in December

Steelers 1-1 (+0 more wins, 2 games played, W1) against Lions on Sundays AWAY in December

Steelers 3-1 (+2 more wins, 4 games played, W3) against Lions all-time won-lost record in December

Steelers 1-1 (+0 more wins, 2 games played, W1) against Lions all-time won-lost record in December AWAY.

The Steelers have never played against the Lions all-time in Week 16, according to Statmuse.com.

The Steelers have never played against the Lions all-time AWAY in Week 16, according to Statmuse.com.

The Steelers against the Lions have a winning percentage at or above .500 for SIX of the above twelve data points. The Steelers against the Lions are currently on a winning streak for SIX of the 12 data points listed above. The Steelers have a combined winning and losing streak against the Lions of W14 based on all of the criteria after the 12 points criteria for each team.

Predicted on Wednesday, December 17th, 2025, at 9:39 p.m. Eastern Time

Prediction to win: Detroit Lions

Prediction to lose: Pittsburgh Steelers

Results:

Sunday, December 21st, 2025

Las Vegas Raiders at Houston Texans, 4:25 p.m. Eastern Time (CBS)

The Las Vegas Raiders all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

511-492-11 (+19 more wins, 1,014 games played, L8) all-time won-lost record REGULAR SEASON

225-274-8 (-49 more wins, 507 games played, L6) all-time won-lost record REGULAR SEASON AWAY

536-512-11 (+24 more wins, 1,059 games played, L8) all-time won-lost record REGULAR SEASON and POSTSEASON

230-288-8 (-58 more wins, 526 games played, L6) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Raiders have a combined winning and losing streak of L28 for the four categories above!

6-3 (+3 more wins, 9 games played, W2) all-time won-lost record on December 21st

1-1 (+0 more wins, 2 games played, L1) all-time on December 21st AWAY

434-413-6 (+21 more wins, 853 games played, L6) all-time won-lost record on Sundays regular season

185-219-4 (-34 more wins, 40i games played, L5) all-time won-lost record on Sundays AWAY regular season

87-100 (-13 more wins, 187 games played, L2) all-time won-lost record on Sundays in December regular season

28-4o (-21 more wins, 77 games played, L1) all-time won-lost record on Sundays in December AWAY regular season

117-124-1 (-6 more wins, 242 games played, L2) all-time won-lost record in December regular season

40-62 (-22 more wins, 102 games played, L1) all-time won-lost record in December AWAY regular season

326-325-5 (+1 more wins, 656 games played, L6) all-time won-lost record against AFC regular season

144-181-3 (-37 more wins, 328 games played, L4) all-time won-lost record against AFC AWAY regular season

19-28 (-9 more wins, 47 games played, L1) all-time won-lost record against AFC South regular season

9-14 (-5 more wins, 23 games played, L4) all-time won-lost record against AFC South AWAY regular season

The Raiders are at or above a .500 winning percentage for FOUR of the 12 categories above. The Raiders have a winning streak for ONE of the 12 categories above. The Raiders have a combined winning and losing streak for the 12 categories above of L31.

The Houston Texans all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

171-214-1 (-43 more wins, 386 games played, W6) all-time won-lost record REGULAR SEASON

97-95-1 (+2 more wins, 193 games played, W3) all-time won-lost record REGULAR SEASON HOME

177-222-1 (-45 more wins, 400 games played, W6) all-time won-lost record REGULAR SEASON and POSTSEASON

103-97-1 (+6 more wins, 201 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Texans have a combined winning and losing streak of W18 for the four categories above!

2-3 (-1 more wins, 5 games played, L1) all-time won-lost record on December 21st

1-1 (+0 more wins, 2 games played, W1) all-time won-lost record on December 21st HOME

153-189-1 (-36 more wins, 343 games played, W5) all-time won-lost record on Sundays regular season

90-85-1 (+5 more wins, 176 games played, W2) all-time won-lost record on Sundays HOME regular season

39-50 (-11 more wins, 89 games played, W5) all-time won-lost record on Sundays in December regular season

21-22 (-1 more wins, 43 games played, W3) all-time won-lost record on Sundays in December HOME regular season

45-59 (-14 more wins, 104 games played, W2) all-time won-lost record in December regular season

24-26 (-2 more wins, 50 games played, W1) all-time won-lost record in December HOME regular season

133-151-1 (-18 more wins, 285 games played, W5) all-time won-lost record against AFC regular season

71-70-1 (+1 more wins, 142 games played, W2) all-time won-lost record against AFC HOME regular season

20-26 (-6 more wins, 46 games played, W1) all-time won-lost record against AFC West regular season

9-14 (-5 more wins, 23 games played, L1) all-time won-lost record against AFC West HOME regular season

The Texans are at or above a .500 winning percentage for THREE of the 12 categories above. The Texans have a winning streak for TEN of the 12 categories above. The Texans have a combined winning and losing streak for the 12 categories above of W25.

Predicted on Wednesday, December 17th, 2025, at 9:46 p.m. Eastern Time

Prediction to win: Las Vegas Raiders

Prediction to lose: Houston Texans

Results:

Sunday, December 21st, 2025, Sunday Night Football

New England Patriots at Baltimore Ravens, 8:20 p.m. Eastern Time (NBC and Peacock)

The New England Patriots before all games in regular season Week 16 in the 2025-26 National Football League season!:

Patriots 556-449-9 (+107 more wins, 1,014 games played, L1) all-time won-lost record REGULAR SEASON

Patriots 247-257-3 (-10 more wins, 507 games played, W6) all-time won-lost record REGULAR SEASON AWAY

Patriots 593-471-9 (+122 more wins, 1,073 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON (I think Statmuse screwed this stat up in Week 11, unless I messed it up!)

Patriots 259-270-3 (-11 more wins, 532 games played, W6) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The Patriots have a winning and losing streak of W10 for the four categories above. The Patriots are 2-0 this season AT LEAST when it is W20 or higher!

Patriots 5-1 (+4 more wins, 6 games played, W5) on December 21st all-time won-lost record

Patriots 3-1 (+2 more wins, 4 games played, W3) all-time won-lost record on December 21st AWAY

Patriots 475-381-6 (+94 more wins, 862 games played, L1) all-time won-lost record REGULAR SEASON on Sundays

Patriots 214-217-2 (-3 more wins, 433 games played, W6) all-time won-lost record REGULAR SEASON on Sundays AWAY

Patriots 107-84 (+23 more wins, 191 games played, L5) all-time won-lost record REGULAR SEASON on Sundays in December

Patriots 51-55 (-4 more wins, 106 games played, L3) all-time won-lost record REGULAR SEASON on Sundays in December AWAY

Patriots 131-105 (+27 more wins, 237 games played, L1) all-time won-lost record REGULAR SEASON in December

Patriots 64-69 (-5 more wins, 133 games played, L3) all-time won-lost record REGULAR SEASON in December AWAY

Patriots 379-284 (+95 more wins, 663 games played, L1) against the AFC all-time in the regular season

Patriots 162-169 (-7 more wins, 331 games played, W4) against the AFC AWAY all-time in the regular season

Patriots 36-11 (+25 more wins, 47 games played, W2) against the AFC North all-time in the regular season

Patriots 16-7 (+9 more wins, 23 games played, W6) against the AFC North AWAY all-time in the regular season

The Patriots have a winning percentage at or above .500 for EIGHT of the above twelve data points. The Patriots are currently on a winning streak for SIX of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals W12.

Baltimore Ravens:

The Baltimore Ravens before all games in regular season Week 16 in the 2025-26 National Football League season!:

275-206-1 (+69 more wins, 482 games played, W1) all-time won-lost record REGULAR SEASON

163-78-1 (+85 more wins, 242 games played, L2) all-time won-lost record REGULAR SEASON HOME

293-220-1 (+73 more wins, 514 games played, W1) all-time won-lost record REGULAR SEASON and POSTSEASON

168-83-1 (+85 more wins, 252 games played, L2) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Ravens have a combined winning and losing streak of L2 for the four categories above!

2-2 (+0 more wins, 4 games played, W1) all-time won-lost record on December 21st

1-0 (+1 more wins, 1 games played, W1) all-time won-lost record on December 21st HOME

235-180-1 (+55 more wins, 416 games played, W1) all-time won-lost record on Sundays regular season

142-71-1 (+71 more wins, 214 games played, L1) all-time won-lost record on Sundays HOME regular season

60-43 (+17 more wins, 103 games played, W1) all-time won-lost record on Sundays in December regular season

42-18 (+42 more wins, 60 games played, L2) all-time won-lost record on Sundays in December HOME regular season

74-49 (+25 more wins, 123 games played, W1) all-time won-lost record in December regular season

49-19 (+30 more wins, 68 games played, L1) all-time won-lost record in December HOME regular season

199-161 (+38 more wins, 360 games played, W1) all-time won-lost record against AFC regular season

118-63 (+55 more wins, 181 games played, L2) all-time won-lost record against AFC HOME regular season

33-25 (+8 more wins, 58 games played, W2) all-time won-lost record against AFC East regular season

22-7 (+15 more wins, 29 games played, W3) all-time won-lost record against AFC East HOME regular season

The Ravens are at or above a .500 winning percentage for TWELVE of the 12 categories above. The Ravens have a winning streak for EIGHT of the 12 categories above. The Ravens have a combined winning and losing streak for the 12 categories above of W5.

Predicted on Wednesday, December 17th, 2025, at 9:47 p.m. Eastern Time

Prediction to win: Baltimore Ravens

Prediction to lose: New England Patriots

Results:

Monday Night Football

San Francisco 49ers at Indianapolis Colts, 8:15 p.m. Eastern Time (ESPN and ABC)

The San Francisco 49ers all-time won-lost records before all games in regular season Week 16 in the 2025-26 National Football League season!:

49ers 602-516-14 (+86 more wins, 1,132 games played, W4) all-time won-lost record REGULAR SEASON

49ers 273-288-6 (-15 more wins, 567 games played, W3) all-time won-lost record REGULAR SEASON AWAY

49ers 640-540-14 (+100 more wins, 1,194 games played, W4) all-time won-lost record REGULAR SEASON and POSTSEASON

49ers 282-302-6 (-20 more wins, 590 games played, W3) all-time won-lost record REGULAR SEASON and POSTSEASON AWAY

The 49ers have a winning and losing streak of W14 for the four categories above.

49ers 2-2 (+0 more wins, 4 games played, L1) on December 21st all-time won-lost record

49ers 0-1 (-1 more wins, 1 games played, L1) all-time won-lost record on December 21st AWAY

49ers 54-32 (+22 more wins, 86 games played, W1) all-time won-lost record REGULAR SEASON on Sundays

49ers 22-16 (+6 more wins, 38 games played, L1) all-time won-lost record REGULAR SEASON on Sundays AWAY

49ers 15-10 (+5 more wins, 25 games played, L3) all-time won-lost record REGULAR SEASON on Sundays in December

49ers 3-2 (+1 more wins, 5 games played, L1) all-time won-lost record REGULAR SEASON on Sundays in December AWAY

49ers 160-106-1 (+54 more wins, 267 games played, W1) all-time won-lost record REGULAR SEASON in December

49ers 60-58 (+2 more wins, 118 games played, L2) all-time won-lost record REGULAR SEASON in December AWAY

49ers 118-101 (+17 more wins, 219 games played, W2) against the AFC all-time in the regular season

49ers 52-57 (-5 more wins, 109 games played, W1) against the AFC AWAY all-time in the regular season

49ers 12-12 (+0 more wins, 24 games played, W1) against the AFC South all-time in the regular season

49ers 5-7 (-2 more wins, 12 games played, L1) against the AFC South AWAY all-time in the regular season

The 49ers have a winning percentage at or above .500 for NINE of the above twelve data points. The 49ers are currently on a winning streak for FIVE of the 12 data points listed above. The combined winning and losing streaks of these twelve data points equals L4.

The Indianapolis Colts all-time won-lost records BEFORE regular season Week 16 in the 2025-26 National Football League season!:

572-515-8 (+56 more wins, 1,095 games played, L4) all-time won-lost record REGULAR SEASON

313-230-5 (+83 more wins, 548 games played, L1) all-time won-lost record REGULAR SEASON HOME

595-541-8 (+54 more wins, 1,144 games played, L4) all-time won-lost record REGULAR SEASON and POSTSEASON

325-238-5 (+87 more wins, 568 games played, L1) all-time won-lost record REGULAR SEASON and POSTSEASON HOME

The Colts have a combined winning and losing streak of L10 for the four categories above!

7-3 (+4 more wins, 10 games played, W4) all-time won-lost record on December 22nd

6-1 (+5 more wins, 7 games played, W3) all-time won-lost record on December 22nd HOME

25-21 (+4 more wins, 46 games played, L5) all-time won-lost record on Mondays regular season

14-8 (+6 more wins, 22 games played, L4) all-time won-lost record on Mondays HOME regular season

3-4 (-1 more wins, 7 games played, L2) all-time won-lost record on Mondays in December regular season

2-1 (+1 more wins, 3 games played, L1) all-time won-lost record on Mondays in December HOME regular season

137-120-2 (+17 more wins, 259 games played, L3) all-time won-lost record in December regular season

79-38-2 (+41 more wins, 119 games played, W3) all-time won-lost record in December HOME regular season

98-104-1 (-6 more wins, 203 games played, L1) all-time won-lost record against NFC regular season

55-44-1 (+11 more wins, 100 games played, W2) all-time won-lost record against NFC HOME regular season

21-28 (-7 more wins, 49 games played, L1) all-time won-lost record against NFC West regular season

13-11 (+2 more wins, 24 games played, W1) all-time won-lost record against NFC West HOME regular season

The Colts are at or above a .500 winning percentage for NINE of the 12 categories above. The Colts have a winning streak for FIVE of the 12 categories above. The Colts have a combined winning and losing streak for the 12 categories above of L4.

Predicted on Wednesday, December 17th, 2025, at 9:50 p.m. Eastern Time

Prediction to win: Indianapolis Colts

Prediction to lose: San Francisco 49ers

Results:

Those are all of my predictions for right now! Be sure to come back to this page for my re-predictions of my NFL original predictions for Regular Season Week 16 (and also to see how many wins and losses I actually get with my original predictions and my re-predictions for Regular Season Week 16) and be sure to come back to this website for my predictions to win and lose for next week (and for every single week after that for the entire 2025-26 National Football League season or until as long as I want to keep making predictions)!

Be sure to follow me on my various social media which you can find on this page for right now. Also, be sure to follow me on Twitter/X @Evan_Troxel. Also, be sure to definitely follow me on Gab @Evan_Troxel as well in case I ever get censored and banned from X and Facebook!

I reserve the right to change my predictions before game time. I also can change my predictions AFTER game time ONLY if I decide BEFORE game time that I want to change my predictions and I just do not have access to the Internet before game time.

LEGAL NOTICE: I DO NOT endorse and I do not encourage people to gamble or bet your own money and other people's money at all! These predictions are not meant to be taken as extremely serious advice for betting and gambling purposes anytime at all in the near future!